Spravato® Nasal Spray
Relief beyond traditional treatments
If traditional antidepressants haven’t provided the relief you need, you’re not alone. At Daydream MD, we offer a new approach to healing. Discover a path toward brighter days with innovative, personalized treatment.
FDA-approved
Evidence-based care
Compassionate team to help
Alternative depression treatment


A simple, three-step process to get started
01
Initial evaluation
Our wellness team reviews your medical history, current symptoms, and previous treatments to determine if Spravato® is the right option for you.
02
Enrollment in the Spravato® program
Once you’re a good fit, we guide you through the required insurance pre-authorization process.
03
Supervised treatment sessions
Begin with eight transformative sessions at our spa-inspired Daydream MD.
Each session includes
Self-administration of Spravato® nasal spray under the guidance of our medical team.
Two hours of relaxation and recovery in a calming, spa-like environment.
Personalized care through ongoing connection with your prescriber to tailor treatment to your unique needs.
Benefits of Spravato over time
Depression and anxiety symptoms


During the introduction phase (weeks 1–4), you’ll attend twice-weekly sessions to quickly manage symptoms. During this time, you’ll follow your personal Spravato protocol with frequent treatments—all designed to keep your goals and greater wellbeing in mind.
In the maintenance phase (weeks 5–8), sessions typically shift to once a week, with further adjustments based on your progress. In phase 02, integrations like talk therapy, yoga, mindfulness, and journaling are far more potent—leading to shifts that last.
FAQs
Why choose Spravato®?
Fast-acting relief: Many patients notice improvements within hours—much faster than traditional antidepressants.
Innovative treatment: Spravato® targets NMDA receptors in the brain, offering a unique approach when other medications haven’t worked.
Enhanced safety: Administered under strict REMS guidelines, every session is monitored by healthcare professionals.
How does Spravato® work?
Spravato® (esketamine) nasal spray works by targeting NMDA receptors, a different pathway from traditional medications that focus on serotonin and norepinephrine. This unique mechanism helps “reset” brain function, providing relief when you may have felt stuck with other treatments.
Who is eligible for Spravato® treatment?
Spravato® is designed for adults with treatment-resistant depression—those who haven’t experienced sufficient relief after trying at least two other antidepressants. Your healthcare provider will review your history and symptoms to determine if Spravato® is the right option for you.
Understanding side effects and safety
Like all medications, Spravato® can have side effects. Common reactions include:
Dizziness
Nausea
Feelings of dissociation (a sense of detachment)
Temporary increases in blood pressure
Proven effectiveness and treatment options
Clinical studies show that many patients experience significant relief with Spravato®, often noticing improvements within hours of administration. When combined with an oral antidepressant, Spravato® has proven highly effective in managing TRD and major depressive disorder.
Cost and insurance coverage
Many insurance plans now cover Spravato®, making this innovative treatment accessible to more patients. At Daydream MD, we can help verify your coverage and guide you through the process.
Spravato® vs. other depression treatments
Less invasive: Unlike ketamine infusions, Spravato® is administered as a nasal spray.
FDA-approved: It is the only nasal spray specifically approved for treatment-resistant depression.
Quick relief: Experience noticeable improvements faster than with traditional therapies such as SSRIs or SNRIs.
Struggling with Treatment-Resistant Depression? There’s Hope.
If other treatments haven’t worked, Spravato® may help.
Our expert team at Daydream MD is here to guide you.
What we get asked about Spravato
What is Spravato® and what is it used for?
Spravato® (esketamine) nasal spray is a fast-acting treatment for adults with treatment-resistant depression. It works differently from traditional antidepressants by targeting NMDA receptors in the brain, offering relief when other treatments have failed.
How quickly does Spravato® work?
Many patients report feeling better within 30 minutes to a few hours after administration.
What can I expect during a session?
You may experience mild disconnection or lightheadedness. Rest assured, you are monitored by a healthcare provider throughout your session for safety.
Is Spravato® addictive?
When taken as prescribed in a clinical setting, Spravato® has a low risk of addiction.
Can I drive after a session?
Due to potential side effects like dizziness, it is recommended that you do not drive for 24 hours after your treatment.
Is Spravato® covered by insurance?
Coverage varies. Many insurance plans, including Medicare, offer coverage. Contact us to check your eligibility.
Start your path to recovery
At Daydream MD, we blend cutting-edge science with a compassionate, personalized approach to help you thrive. Let our expert team guide you on your journey to better mental health.
Contact us now to learn more about Spravato®.

